Endocrine Abstracts

Toll-like receptor 4 (TLR-4) plays an important role in innate immunity. Changes in the reduction–oxidation balance of tissues can lead to a pro-inflammatory state and insulin resistance typically seen in diabetes. An action thought to be mediated by TLRs. Omega-3 fatty acids and peroxisome proliferator activated receptor gamma (PPAR-γ) agonists as pioglitazone are currently used for decreasing inflammation in diabetes.Aim: The aim of this stud...